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Class 4 Cold Laser research

 

95% EFFECTIVENESS AT RELIEF OF NECK PAIN; RECURRENCE OF PAIN 58% IN PLACEBO GROUP, BUT ONLY 14% IN LASER TREATED GROUP
Soriano et al, Laser Therapy, 1996 (8) pp 149-154

 

PERIPHERAL NEUROPATHY
After treatment, there was an improvement of 71%. Only 43% continued to have loss of protective sensation. Light treatment associated with a reduced incidence of diabetic foot wounds and amputations
J Am Podiatr Med Assoc. 2005 Mar-Apr; 95 (2)

 

LASER THERAPY IMPROVED SPATIAL PERCEPTION, IMPROVED NERVE FUNCTION, IMPROVED EMG STUDY OUTCOMES.
Laser can regenerate nerve tissue.
Peric Z, Srp Arh Celok Lek 2007 May-Jun; 135 (5-6): 257-63

 

BONE REGENERATION IN DENTISTRY AND MEDICINE
Laser improves osteoblastic formation, bone strength in fractures, implant stability, and can improve osteonecrosis of the jaw.
Lasers Med Sci. 2010 Jul; 25(4): 559-69). Photomed Laser Surg. 2010 Jun; 28(3): 365-9 Lasers Surg Med 2009 Apr;41(4):298-304
J Orthop Surg Res. 2010 Jan 4;5(1):1

 

CARPAL TUNNEL BETTER WITH LASER
LLL better than splinting
Clinical Rheumatology (2009 Sep;28 (9):1059-65

 

CARTILAGE REGENERATION
Laser therapy significantly enhanced the stiffness of the cartilage after approximately 8 weeks of treatment. Laser therapy has ability to regenerate damaged cartilage.

MUSCLE PERFORMANCE BETTER WITH LASER
Laser increases strength of muscles during exercise
Lasers Med Sci. 2010 Nov 18

 

FROZEN SHOULDER BENEFITS
A significant improvement in laser therapy compared to the control group. The treatment group experienced significantly less pain and significantly improved disability scores. Range of motion in the treatment group was better than placebo.
Photomed Laser Surg. 2008 Mar 16.

 

NERVE GROWTH STIMULATION
Contolled trial showed regeneraton of sciatic nerve and myelination in rat.
Rochkind. Photomed & Laser Surg. 2007, 25(3): 137-143.

 

MITOCHONDRAL FUNCTION IMPROVED
Improves oxygen production, promoting cellular survival, Increased Cytochrome c oxidase – terminal enzyme of the electron transport chain and a strong photacceptor and other mitochondral enzymes
J Photochem Photobiol B. 2006 Nov 17

 

TENDINITIS AND MYOFASCIAL PAIN BENEFITS
Acute tendinitis had the best response
Logdberg-Anersson et al, Laser Therapy 1997 (9) pp 79-86

TREATMENT OF THE STELLATE GANGLION POSITIVELY AFFECTS THE SYMPATHETIC NERVOUS SYSTEM
Kemmotsu. Laser Therapy 1997 (9) pp 5-6

 

TRIGEMINAL NEURALGIA BENEFITS
Statistically significant difference to pain relief with reduced consumption of analgesics in 60% of pts whose treatment was successful was maintained at 1 year follow up
Eckerdal & Bastian Laser Therapy 1996 (8) pp 247-52

 

TENDINOPAYTH BENEFITS
Treatment affects degenerative changes in tendon matrix/collagen production and inflammation.  The mean effect over placebo was 32%. Optimal treatment intervals: daily or every other day for 2-4 weeks
Bjordal et al, Physical Therapy Reviews 2001

 

6% OF PHOTONS REACH SPINAL CORD
Applied directly to AP of porcine subjects; 6% of photons reached cord and increased CGRP/mRNA
Kimberly Byrnes, PhD, NAALT, 2003/2004

 

NERVE HEALING
Desensitizes C-fibers
INCREASED: Conduction latency, Schwann cell product, Nerve cell metabolism, Nerve process sprouting
DECREASED: Neural scarring and nerve microtubules, Retrograde posttraumatic degeneration, Multiple nerve discharge
Rochkind S, Photomed Laser Surg. 2006 Jun;24 (2):121-128

 

NON-STEROIDALS: COMPARABLE EFFECTS
Laser as effective as NSAIDs
Bjordahl J, Photomed Laser Surg. 2006 Jun; 24 (2):158-168
BLOOD PRESSURE LOWERED WITH LASER
Laser applied to acupoints lowered blood pressure
J of Chiro Med, 2008 Dec; 7 (4):134-9

 

CANCER RISK NOT INCREASED WITH LOW LEVEL LASERS
A 25 year follow up showed no increase in mortality when cancer patients were treated with low level lasers
Vopr Kurortol Fizioter Lech Fiz Kult. 2009 Nov-Dec; (6):49-52

 

TEMPORMANDIBULAR JOINT (TMJ)
Decreased of pain and anti-inflammatory effects; Confirmed by thermographic examination.
Photomed Laser Surg. 2006 Aug;24 (4):522-7

 

CORTISONE HAS SIMILAR EFFECTS AS LASER
Animal study; 810-nm laser was almost as good as cortisone at reducing swelling. Higher doses showed most benefit.  Laser therapy reduced joint swelling and correlated with decreased serum prostaglandins
Castano AP, Lasers Surg Med 2007 Jul;39(6):543-50

 

ULTRASOUND vs. LASER
Animal study; laser treatment provided a much greater increase in the wound strength than ultrasound.
J Rehab Res & Dev, Volume 41 Number 5, September/October 2004

 

LOW-LEVEL LASER THERAPY VS LOW-INTENSITY PULSED ULTRASOUND (LIPUS)
LIPUS enhanced bone repair by promoting bone resorption; LLLT accelerated this process through bone formation.
Photomed Laser Surg. 2006 Dec; 24 (6):735-40

 

STROKE HELPED WITH LASER
Laser applied to skull improves brain following stroke
Curr Cardiol Rep. 2010 Jan; 12 (1):29-33

 

PSYCHIATRIC DISORDERS IMPROVED
LLL applied to skull decreased depression and anxiety.
Behavioral and Brain Functions, 2009, 5:46, 8 December 2009

 

PHYSIOLOGICAL BENEFITS
INCREASES: cell proliferation, cell division, cell maturation, secretion of growth factors, wound healing, collagen production, wound strength, wound closer, fibroblasts, myofibroblasts, chondrocytes, epithelialization, skin circulation, oxygen supply, activity satellite cell cultures (stem cells)
DECREASES: Prostaglandin E2, substance P, cyclooxygenase 2 (Cox 2), muscle tension
J Clin Las Med Surg 2004; 22 (2) 141-150


THYROID FUNCTION IMPROVES
Laser improves the function of the thyroid based on lab values with chronic autoimmune thyroiditis.
Lasers Surg Med. 2010 Aug;42 (6):589-96

CELLULAR BENEFITS
INCREASES: mitochondria and ATP production, cytochrome oxiase and singlet oxygen, tissue regeneration genes and motor proteins, RNA DNA synthesis, growth factors, cell metabolism, angiogenesis, and mitosis
Desmet K, et al. Photomed Laser Surg. 2006 Jun; 24 (2):121-128

 

CORTISONE IMPROVED WITH LLLT
Laser plus cortisone more effective than cortisone by itself
Photomed Laser Surg. 2010 Oct;28 (5):639-46

 

CARDIAC MUSCLE BENEFITS
Laser doubles the rate of muscle regeneration in ischemia reperfusion injuries. Laser reduced scar tissue post MI by 70%; Dramatic stimulation of satellite and stem cells. Increased Heat Shock Prot and anti-oxidants
Oron U. Photomed Las Surg. 2006; 24 (2):111-120

 

FRACTURES
Laser creates an increase in Osteoblasts & Calcium
Pinheiro L, Photomed Laser Surg. 2006 Jun;24 (2):169-171

 

ACHILLES TENDINITIS
Prostaglandin E2 concentrations were significantly reduced. Pressure pain threshold had increased significantly and reduced inflammation and pain
Br J Sports Med. 2006 Jan;40 (1):76-80; discussion 76-80.

 

PARKINSON’S IMPROVED WITH LASER
LLL improves nerve function with Parkinson’s
Molecular Degen 2009 Jun 17;4:26

 

STROKE
Animal study; Neurological deficits improved
Lasers Surg Med. 2006 Jan;38 (1):70-3.
Stroks. 2006 Oct;37 (10):2620-4.

 

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Class 4 Cold Laser Research

 

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